NutriStack
Symptom·Immune·Reviewed May 30, 2026
Supplements for Recurrent cold sores.
When recurrent cold sores is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01L-LysineModerate84% match
L-lysine shifts the lysine to arginine ratio, modestly reducing HSV outbreak frequency in long-term users.
SuggestedL-lysine HCl, 1 to 3 g per day for prevention; higher during outbreaks - 02ZincLimited66% match
Topical and oral zinc support antiviral mucosal defense; serum zinc supports immune function.
SuggestedZinc picolinate, 15 to 30 mg per day; topical zinc oxide on lesions - 03Vitamin CLimited58% match
Vitamin C supports immune function and modestly shortens viral illness duration when started early.
SuggestedAscorbic acid, 1 to 2 g per day at first prodrome - 04Vitamin D3Limited50% match
Vitamin D modulates antiviral mucosal immunity and may reduce HSV reactivation frequency.
SuggestedVitamin D3, 2000 to 5000 IU per day adjusted by 25(OH)D
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