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Symptom·Appearance·Reviewed May 30, 2026

Supplements for Vitiligo (depigmentation) adjunctive support.

When vitiligo (depigmentation) adjunctive support is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.

Matches7 supplementsStrong evidence0 of 7Last reviewedMay 30, 2026
Supplements

Ranked by relevance, top first.

Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.

  1. 01
    Vitamin D3Limited
    66% match

    Vitamin D modulates skin immune activity and melanocyte function, and low status is common in vitiligo, so repletion is a rational adjunct to phototherapy.

    SuggestedD3 (cholecalciferol) softgel
  2. 02
    Vitamin B12Limited
    60% match

    Combined oral vitamin B12 plus folate has shown some repigmentation benefit, particularly when paired with sun or UV exposure, in small studies.

    SuggestedMethylcobalamin (B12), taken with folate
  3. 03
    Vitamin B9Limited
    57% match

    Folate works with B12 in the studied repigmentation protocols and supports the methylation pathways involved in melanocyte health.

    SuggestedFolate (or methylfolate) tablet
  4. 04
    Ginkgo BilobaLimited
    55% match

    Ginkgo's antioxidant and immunomodulatory actions have shown arrest of spread and some repigmentation in small randomized trials of slowly progressing vitiligo.

    SuggestedStandardized Ginkgo biloba extract capsule
  5. 05
    Alpha-Lipoic AcidLimited
    50% match

    Alpha-lipoic acid is an antioxidant that, combined with narrowband UVB and other antioxidants, improved repigmentation versus phototherapy alone in a small trial, targeting the oxidative stress on melanocytes.

    SuggestedAlpha-lipoic acid capsule
  6. 06
    Vitamin CLimited
    45% match

    Vitamin C is an antioxidant included in combination antioxidant regimens aimed at reducing the oxidative melanocyte damage implicated in vitiligo.

    SuggestedVitamin C tablet (with food)
  7. 07
    Vitamin ELimited
    42% match

    Vitamin E is a lipid-phase antioxidant used within combination antioxidant protocols to protect melanocytes from oxidative stress during phototherapy.

    SuggestedMixed tocopherol softgel

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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.