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Supplement × Prescription·Evidence index

Albuterol and Potassium: what the research found

PubMed indexes 8 records that name Albuterol and Potassium together, either in the title or in an interaction, co-administration, or pharmacokinetic context. The key findings come first, in the authors’ own words, followed by every study with its design and PubMed link.

A summary of published research, not medical advice. A pharmacist can check any combination against your full list of medicines and supplements.

Key findings

What the studies concluded.

Reviews and human studies first. Each quote is the authors’ own conclusion about their study, not a NutriStack assessment, and a single study is not a consensus.

“Transcellular shifts of potassium, as in the case of albuterol toxicosis, can lead to rebound hyperkalemia even after discontinuation of potassium supplementation. This case further explores the utility of fractional excretion of electrolytes in elucidating the etiology and management of electrolyte disturbances.”

Guida et al. · 2023 · Human study · details

“Albuterol IH decreases blood potassium concentrations in a dose-dependent manner without clinically meaningful alterations to heart rate or blood glucose concentrations in healthy dogs. The mean decrease in potassium concentration at the high-dose of albuterol was modest (0.38 mmol/L).”

Ogrodny et al. · 2022 · Human study · details

“Nebulized albuterol increases lactate levels and decreases potassium levels in healthy adults.”

The research

8 studies naming Albuterol and Potassium.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Rebound hyperkalemia in a dog with albuterol toxicosis after cessation of potassium supplementation.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2023 · PMID 37943086

Case ReportsHuman subjects

“Transcellular shifts of potassium, as in the case of albuterol toxicosis, can lead to rebound hyperkalemia even after discontinuation of potassium supplementation. This case further explores the utility of fractional excretion of electrolytes in elucidating the etiology and management of electrolyte disturbances.”

Guida et al. · From the abstract

Names both Albuterol and Potassium in its title.

Effect of Nebulized Albuterol on Serum Lactate and Potassium in Healthy Subjects.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2016 · PMID 26857949

Randomized Controlled Trial

“Nebulized albuterol increases lactate levels and decreases potassium levels in healthy adults.”

Zitek et al. · Authors' conclusion

Names both Albuterol and Potassium in its title.

Salbutamol effects on systemic potassium dynamics during and following intense continuous and intermittent exercise.

European journal of applied physiology · 2016 · PMID 27771799

Randomized Controlled Trial

“Inhaled salbutamol modulated the [K+]a rise across the trial, comprising intense continuous and intermittent exercise and recovery, lowering Δ[K+] during HIcont. The limited [K+]a changes during HIint suggest that salbutamol is unlikely to influence systemic [K+] during periods of intense effort in intermittent sports.”

Altarawneh et al. · Authors' conclusion

Names both Albuterol and Potassium in its title.

Effect of inhaled albuterol on whole blood potassium concentrations in dogs.

Journal of veterinary internal medicine · 2022 · PMID 36178135

Human subjects

“Albuterol IH decreases blood potassium concentrations in a dose-dependent manner without clinically meaningful alterations to heart rate or blood glucose concentrations in healthy dogs. The mean decrease in potassium concentration at the high-dose of albuterol was modest (0.38 mmol/L).”

Ogrodny et al. · Authors' conclusion

Names both Albuterol and Potassium in its title.

Effect of Aerosolised Salbutamol Administration on Arterial Potassium Concentration in Anaesthetised Horses.

Journal of equine veterinary science · 2021 · PMID 34281643

Animal study

“The reduction in [K +] between baseline and the second electrolyte measurement was significantly greater in group S (12.3%) compared to group NS (6.9%) (P= .017) and was significantly associated with salbutamol administration (P= .04). The results of this study indicate that monitoring [K +] is important in anaesthetized horses, particularly after aerosolized salbutamol administration.”

Loomes · From the abstract

Names both Albuterol and Potassium in its title.

Nebulized salbutamol for asthma: effects on serum potassium and phosphate levels at the 60 min.

Revista portuguesa de pneumologia · 2013 · PMID 23659992

Human subjects

“Administration of nebulized salbutamol during the emergency treatment of acute exacerbation of asthma is not associated with a statistical decrease in serum phosphate. There was significant hypokalemia. This study indicates that a further study is needed to elucidate the clinical significance of nebulized salbutamol on serum phosphate.”

Sahan et al. · Authors' conclusion

Names both Albuterol and Potassium in its title.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

How to read this page

A literature summary, not guidance.

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Albuterol, Potassium, and several hundred other substances.

Log your routine, get reminders at the times you choose, and scan a label to add a product. The checker is a research and organisation tool, not a clinical decision aid.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.