Tedisamil and dofetilide-induced torsades de pointes, rate and potassium dependence.
“6. The results suggest that tedisamil, like dofetilide, presents a risk for development of torsades de pointes.”
Names both Dofetilide and Potassium in its title.
Supplement × Prescription·Evidence index
PubMed indexes 4 records that name Dofetilide and Potassium together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.
Every statement below is attributed to a named, dated, linked source.
This page lists published research relevant to Dofetilide and Potassium. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.
Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.
“6. The results suggest that tedisamil, like dofetilide, presents a risk for development of torsades de pointes.”
Names both Dofetilide and Potassium in its title.
“Patients who received nonstandard initial doses of dofetilide or sotalol had 4.7 times greater odds of experiencing a safety-related event requiring dose reduction or discontinuation. Conclusion: Following package insert dosing in elderly patients increases safety and tolerability relative to more aggressive dosing of dofetilide or sotalol.”
Names Dofetilide and Potassium together in an interaction, co-administration, or pharmacokinetic context.
“We conclude that dofetilide prolongs QTc interval duration in a concentration-dependent manner in normal volunteers during sinus rhythm and that pharmacokinetic-pharmacodynamic modeling is useful for examination of maximum QTc prolongation induced by dofetilide.”
Names Dofetilide and Potassium together in an interaction, co-administration, or pharmacokinetic context.
Names Dofetilide and Potassium together in an interaction, co-administration, or pharmacokinetic context.
Search-based evidence indexes have real limits, and it is worth being explicit about them:
NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Dofetilide, Potassium, and several hundred other substances.
The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.