From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyModerate evidence
What is happening. Both increase nitric oxide availability and may additively lower blood pressure.
Mechanism. Nitrate-nitrite-NO pathway plus arginine-NO synthase substrate support.
Recommendation. Monitor dizziness and blood pressure when combining.
Stack Score
How it moves the number.
Effect on the composite score
If both Beetroot Extract (Dietary Nitrate) and L-Citrulline are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1McMahon NF et al. Nitrate supplementation meta-analysis. Sports Med. 2017.Needs sourceNo link