Effects of Citrulline Malate Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis.
Systematic ReviewMeta-AnalysisReviewHuman subjects
Names both Citrulline Malate and L-Citrulline in its title.
Supplement × Supplement·Evidence index
PubMed indexes 8 records that name Citrulline Malate and L-Citrulline together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.
Every statement below is attributed to a named, dated, linked source.
This page lists published research relevant to Citrulline Malate and L-Citrulline. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.
Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.
Names both Citrulline Malate and L-Citrulline in its title.
“The mean effects were similar for "limbs" (upper vs lower) [p = 0.763]. Accordingly, our findings suggest that citrulline malate supplementation does not improve muscle strength in healthy and resistance-trained individuals (PROSPERO registration number: CRD42020159338).”
Names both Citrulline Malate and L-Citrulline in its title.
Names both Citrulline Malate and L-Citrulline in its title.
Names both Citrulline Malate and L-Citrulline in its title.
“Six weeks of CM supplementation combined with multicomponent training was associated with improved sit-to-stand performance in older women, with additional favourable trends in walking endurance, SPPB score, and 25(OH)D. Given the pilot nature of the study, these findings should be considered preliminary and hypothesis-generating. Larger and longer trials are needed to confirm the reproducibility, clinical significance, and potential mechanisms of these effects.”
Names both Citrulline Malate and L-Citrulline in its title.
Names both Citrulline Malate and L-Citrulline in its title.
Names both Citrulline Malate and L-Citrulline in its title.
Names both Citrulline Malate and L-Citrulline in its title.
Search-based evidence indexes have real limits, and it is worth being explicit about them:
NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Citrulline Malate, L-Citrulline, and several hundred other substances.
The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.