Supplement × Supplement·a caution·Insufficient evidence
Both affect nitric oxide or vascular pathways, but agmatine may modulate nitric oxide synthase unpredictably.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. Both affect nitric oxide or vascular pathways, but agmatine may modulate nitric oxide synthase unpredictably.
Mechanism. Citrulline raises arginine availability while agmatine modulates nitric oxide synthase and imidazoline receptors.
Recommendation. Start separately and monitor blood pressure, headache, and dizziness.
Effect on the composite score
If both Agmatine Sulfate and L-Citrulline are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
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