NutriStack
Coenzyme Q10 and Vitamin E, a synergy.
CoQ10 (ubiquinol form) regenerates vitamin E from its oxidized form in cell membranes, similar to how vitamin C regenerates vitamin E.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Coenzyme Q10 and Vitamin E
- Pair type
- Synergy
- Evidence (highest tier)
- Moderate
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Moderate evidence
Synergy
What is happening. CoQ10 (ubiquinol form) regenerates vitamin E from its oxidized form in cell membranes, similar to how vitamin C regenerates vitamin E.
Mechanism. Ubiquinol (reduced CoQ10) donates a hydrogen atom to the tocopheroxyl radical, regenerating alpha-tocopherol within lipid membranes. This extends vitamin E's chain-breaking antioxidant activity.
Recommendation. Take together for enhanced membrane antioxidant protection.
Sources (2)
- Kagan VE et al. Recycling and redox cycling of phenolic antioxidants. Ann N Y Acad Sci. 1998
- Bayu P, Wibisono JJ. Vitamin C and E antioxidant supplementation may significantly reduce pain symptoms in endometriosis: A systematic review and meta-analysis of randomized controlled trials. PLoS One. 2024. PMID 38820340
Stack Score
How this pair moves the number.
Effect on the composite score
If both Coenzyme Q10 and Vitamin E are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
Check your full routine
One pair was the worked example. NutriStack runs every pair in your stack at once.
Drop in your supplements and prescriptions and the public database surfaces every interaction, synergy, timing rule, and contraindication, every one linked to its primary source.