NutriStack
Beta-Carotene and Vitamin E, a synergy.
Beta-carotene and vitamin E are complementary antioxidants that protect different cellular compartments, and vitamin E can help protect beta-carotene from oxidative degradation.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Beta-Carotene and Vitamin E
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Beta-carotene and vitamin E are complementary antioxidants that protect different cellular compartments, and vitamin E can help protect beta-carotene from oxidative degradation.
Mechanism. Vitamin E is a lipid-phase chain-breaking antioxidant that quenches peroxyl radicals and can spare beta-carotene from oxidation, while beta-carotene scavenges singlet oxygen, giving complementary antioxidant coverage in lipid membranes.
Recommendation. This combination is generally compatible at normal dietary supplement doses. Avoid very high-dose antioxidant stacking, particularly in smokers, and seek advice if you smoke.
Sources (2)
- Palozza P, Krinsky NI. Beta-carotene and alpha-tocopherol are synergistic antioxidants. Archives of Biochemistry and Biophysics, 1992.
- Bohm F, et al. Carotenoids enhance vitamin E antioxidant efficiency. Journal of the American Chemical Society, 1997.
Stack Score
How this pair moves the number.
Effect on the composite score
If both Beta-Carotene and Vitamin E are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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