Can I take Vitamin A and Vitamin E together?

Yes. The combination of Vitamin A and Vitamin E produces a measurable benefit. Vitamin E protects vitamin A from oxidation in the gut, increasing its absorption and stability.

What kind of interaction is it?

Synergy: a documented combination effect that is stronger or more useful than either substance taken alone.

Is this interaction backed by published research?

Yes. NutriStack lists 3 citation rows for the Vitamin A + Vitamin E pair, each linking to PubMed by PMID where available. Full sourcing methodology at https://nutristackapp.com/methodology/interactions.

Interaction databaseSupplement × SupplementReviewed May 2026

Vitamin A and Vitamin E, a synergy.

Q: How does this affect a NutriStack Stack Score?

+2 to your Stack Score per scored synergy row.

Vitamin E protects vitamin A from oxidation in the gut, increasing its absorption and stability.

3 primary source citations. Moderate evidence. Last verified May 30, 2026.

Open the interaction checker →Read the methodology

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

Sourcing standards·Evidence tiers

From the interaction database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances: Vitamin A and Vitamin E
Pair type: Synergy
Evidence (highest tier): Moderate
Source citations: 3 sources
Stack Score effect: +2 to your Stack Score (per scored synergy row).
Scope: Supplement × Supplement
Last verified: May 30, 2026

Synergy · Moderate evidence

Synergy

What is happening. Vitamin E protects vitamin A from oxidation in the gut, increasing its absorption and stability.

Mechanism. Alpha-tocopherol acts as a chain-breaking antioxidant in the intestinal lumen, preventing oxidative destruction of retinol and retinyl esters before absorption.

Recommendation. Taking together is beneficial. Vitamin E preserves vitamin A activity.

Sources (3)

Combs GF Jr. The Vitamins: Fundamental Aspects in Nutrition and Health. Academic Press. 2012
Xia J, Yu J, Xu H et al.. Comparative effects of vitamin and mineral supplements in the management of type 2 diabetes in primary care: A systematic review and network meta-analysis of randomized controlled trials. Pharmacological Research. 2023. PMID 36638933
Bayu P, Wibisono JJ. Vitamin C and E antioxidant supplementation may significantly reduce pain symptoms in endometriosis: A systematic review and meta-analysis of randomized controlled trials. PLoS One. 2024. PMID 38820340

Stack Score

How this pair moves the number.

Effect on the composite score

If both Vitamin A and Vitamin E are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

Check your full routine

One pair was the worked example. NutriStack runs every pair in your stack at once.

Drop in your supplements and prescriptions and the public database surfaces every interaction, synergy, timing rule, and contraindication, every one linked to its primary source.

Open the interaction checker →Browse the full research index