NutriStack
Collagen Peptides and Hyaluronic Acid, a synergy.
Both support extracellular matrix integrity in skin and joints; combined use has additive evidence for skin hydration and elasticity.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Collagen Peptides and Hyaluronic Acid
- Pair type
- Synergy
- Evidence (highest tier)
- Moderate
- Source citations
- 1 source
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Moderate evidence
Synergy
What is happening. Both support extracellular matrix integrity in skin and joints; combined use has additive evidence for skin hydration and elasticity.
Mechanism. HA provides extracellular water binding and lubrication; collagen peptides supply hydroxyproline and glycine for matrix synthesis.
Recommendation. Common combination: hyaluronic acid 120 to 240 mg plus collagen peptides 10 to 15 g per day.
Sources (1)
- Czajka A et al. Daily oral supplementation with collagen peptides combined with vitamins and other bioactive compounds improves skin elasticity and has a beneficial effect on joint and general wellbeing. Nutr Res. 2018
Stack Score
How this pair moves the number.
Effect on the composite score
If both Collagen Peptides and Hyaluronic Acid are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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