NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

Collagen Peptides and Hyaluronic Acid: what the published research says

PubMed indexes 6 records that name Collagen Peptides and Hyaluronic Acid together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Collagen Peptides and Hyaluronic Acid. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

6 studies naming Collagen Peptides and Hyaluronic Acid.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Nonsurgical Chin Augmentation Using Hyaluronic Acid: A Systematic Review of Technique, Satisfaction, and Complications.

Aesthetic plastic surgery · 2023 · PMID 37036507

Systematic ReviewHuman subjects917 participants

“HA filler is an effective temporary method to correct chin retraction and absorption for chin augmentation, with a high degree of patient satisfaction and a low risk of severe complications.”

Ou et al. · Authors' conclusion

Names Collagen Peptides and Hyaluronic Acid together in an interaction, co-administration, or pharmacokinetic context.

Combination therapy for exacerbations of pain in osteoarthritis with non-fixed combinations

Terapevticheskii arkhiv · 2025 · PMID 40561485

Randomized Controlled TrialClinical Trial, Phase IV

“The combination of CS/GL/MSM/HA with collagen significantly outperforms collagen-free therapy in reducing pain, improving joint function, and decreasing symptomatic treatment needs in patients with knee OA exacerbations. These findings support the inclusion of collagen in OA combination therapy.”

Naumov et al. · Authors' conclusion

Names Collagen Peptides and Hyaluronic Acid together in an interaction, co-administration, or pharmacokinetic context.

Early periodontal wound healing after chlorhexidine rinsing: a randomized clinical trial.

Clinical oral investigations · 2024 · PMID 38833009

Randomized Controlled Trial

“The usage of CHX-ADS following periodontal surgery improved early wound healing, reduced plaque accumulation and gingival inflammation. During the early post-operative period the adjunct of HA further improved soft tissue closure.”

Graziani et al. · Authors' conclusion

Names Collagen Peptides and Hyaluronic Acid together in an interaction, co-administration, or pharmacokinetic context.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Collagen Peptides, Hyaluronic Acid, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.