NutriStack
Astaxanthin and Hyaluronic Acid, a synergy.
Astaxanthin reduces oxidative stress that drives hyaluronic acid breakdown, helping preserve skin hydration and elasticity when paired with supplemental hyaluronic acid.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Astaxanthin and Hyaluronic Acid
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Astaxanthin reduces oxidative stress that drives hyaluronic acid breakdown, helping preserve skin hydration and elasticity when paired with supplemental hyaluronic acid.
Mechanism. Astaxanthin is a potent carotenoid antioxidant that quenches reactive oxygen species and dampens UV-induced matrix metalloproteinase and hyaluronidase activity, slowing degradation of dermal hyaluronic acid that supplementation aims to replenish.
Recommendation. Can be combined in skin-health protocols (for example astaxanthin 4 to 12mg with oral hyaluronic acid 80 to 120mg daily). No separation needed.
Sources (2)
- Tominaga K, et al. Protective effects of astaxanthin on skin deterioration. Journal of Clinical Biochemistry and Nutrition. 2017
- Davinelli S, Nielsen ME, Scapagnini G. Astaxanthin in skin health, repair, and disease: a comprehensive review. Nutrients. 2018
Stack Score
How this pair moves the number.
Effect on the composite score
If both Astaxanthin and Hyaluronic Acid are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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