From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Prescription
Last verified
June 4, 2026
CautionEmerging evidence
What is happening. Quercetin may inhibit CYP3A4 or P-glycoprotein and could increase cyclosporine exposure and nephrotoxicity.
Mechanism. Potential CYP3A4/P-glycoprotein inhibition increases cyclosporine exposure.
Recommendation. Avoid high-dose quercetin unless transplant clinicians monitor trough levels and kidney function.
Stack Score
How it moves the number.
Effect on the composite score
If both Cyclosporine and Quercetin are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1U.S. National Library of Medicine. Cyclosporine Capsules Modified US Prescribing Information. 2026.Needs sourceNo link