Ginkgo Biloba and Serrapeptase, a caution.
Ginkgo inhibits platelet-activating factor and serrapeptase is fibrinolytic, so combining them can additively impair hemostasis and increase the risk of bruising and bleeding.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Ginkgo Biloba and Serrapeptase
- Pair type
- Caution
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- −5 to your Stack Score (per scored caution row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Caution · Emerging evidence
Caution
What is happening. Ginkgo inhibits platelet-activating factor and serrapeptase is fibrinolytic, so combining them can additively impair hemostasis and increase the risk of bruising and bleeding.
Mechanism. Ginkgo terpenoids (ginkgolides) antagonize platelet-activating factor and reduce platelet aggregation, while serrapeptase breaks down fibrin and has reported antithrombotic effects, producing an additive reduction in clotting capacity.
Recommendation. Combine cautiously and monitor for bleeding signs. Avoid the combination with anticoagulants or antiplatelet drugs unless supervised, and stop both at least 7 to 10 days before surgery.
Sources (2)
Stack Score
How this pair moves the number.
Effect on the composite score
If both Ginkgo Biloba and Serrapeptase are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
Check your full routine
One pair was the worked example. NutriStack runs every pair in your stack at once.
Drop in your supplements and prescriptions and the public database surfaces every interaction, synergy, timing rule, and contraindication, every one linked to its primary source.