Supplement × Prescription·a synergy·Moderate evidence
Magnesium supplementation may help correct low magnesium during PPI therapy, but severe PPI-associated hypomagnesemia can require stopping the PPI.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. Magnesium supplementation may help correct low magnesium during PPI therapy, but severe PPI-associated hypomagnesemia can require stopping the PPI.
Mechanism. Supplementation replaces magnesium while rabeprazole may impair intestinal absorption in susceptible patients.
Recommendation. Check serum magnesium if symptoms or risk factors are present; do not rely on supplements alone for severe hypomagnesemia.
Effect on the composite score
If both Magnesium Glycinate and Rabeprazole are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
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