NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Prescription·Evidence index

Methylprednisolone and Potassium: what the published research says

PubMed indexes 6 records that name Methylprednisolone and Potassium together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Methylprednisolone and Potassium. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

6 studies naming Methylprednisolone and Potassium.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Effects of aquaporin 4 and inward rectifier potassium channel 4.1 on medullospinal edema after methylprednisolone treatment to suppress acute spinal cord injury in rats.

Acta cirurgica brasileira · 2018 · PMID 29513816

Animal study

“Methylprednisolone inhibited medullospinal edema in rats with acute spinal cord injury, possibly by reducing the coexpression of aquaporin 4 and Kir4.1 in medullospinal tissues.”

Li et al. · Authors' conclusion

Names both Methylprednisolone and Potassium in its title.

Coexistence of Graves' disease with acute rheumatic fever treated as thyroid storm in young Thai patient.

Journal of pediatric endocrinology & metabolism : JPEM · 2023 · PMID 37060353

Case ReportsHuman subjects

“We reported Graves' disease patients with acute rheumatic fever simulating a thyroid storm. The underlying cardiac disease must be considered, especially where chorea and congestive heart failure are present.”

Onsoi et al. · Authors' conclusion

Names Methylprednisolone and Potassium together in an interaction, co-administration, or pharmacokinetic context.

Cyclosporin A in nephrotic syndrome of childhood--a 14 month experience.

The International journal of pediatric nephrology · 1986 · PMID 3522457

Clinical Trial

“Two of the steroid resistant cases healed. There was a modest incidence of CsA toxicity as evidenced by the usual clinical monitoring and by evaluation of creatinine clearance, plasma potassium and evolution of renal parenchymal cells as studied in the course of sequential fine needle aspiration biopsies.”

Capodicasa et al. · From the abstract

Names Methylprednisolone and Potassium together in an interaction, co-administration, or pharmacokinetic context.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Methylprednisolone, Potassium, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.