NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Prescription·Evidence index

Rosuvastatin and Vitamin B3: what the published research says

PubMed indexes 4 records that name Rosuvastatin and Vitamin B3 together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Rosuvastatin and Vitamin B3. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

4 studies naming Rosuvastatin and Vitamin B3.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Rosuvastatin alone or with extended-release niacin: a new therapeutic option for patients with combined hyperlipidemia.

Preventive cardiology · 2004 · PMID 15539964

Clinical TrialRandomized Controlled Trial

“Rosuvastatin monotherapy was better tolerated than ER niacin taken either alone or with rosuvastatin. In this study, rosuvastatin very effectively improved the three major lipoprotein-lipid abnormalities of combined hyperlipidemia.”

Capuzzi et al. · From the abstract

Names both Rosuvastatin and Vitamin B3 in its title.

Comparison table: Some lipid-lowering drugs.

The Medical letter on drugs and therapeutics · 2019 · PMID 30845107

Comparative StudyHuman subjects

Names Rosuvastatin and Vitamin B3 together in an interaction, co-administration, or pharmacokinetic context.

Comparative effects on lipid levels of combination therapy with a statin and extended-release niacin or ezetimibe versus a statin alone (the COMPELL study).

Atherosclerosis · 2007 · PMID 17239888

Multicenter StudyRandomized Controlled Trial292 participants

“No drug-related myopathy or hepatotoxicity was observed. In this study, low to moderate dose combination therapy with a statin and niacin ER provided broad control of lipids and lipoproteins independently associated with CHD.”

McKenney et al. · From the abstract

Names Rosuvastatin and Vitamin B3 together in an interaction, co-administration, or pharmacokinetic context.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Rosuvastatin, Vitamin B3, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.