Symptom·Digestive·Reviewed May 30, 2026
Supplements for Diarrhea.
When diarrhea is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01Saccharomyces BoulardiiStrong90% match
This non-pathogenic yeast may shorten the duration of acute and antibiotic-associated diarrhea by competing with pathogens and supporting the gut barrier.
SuggestedSaccharomyces boulardii CNCM I-745 capsules - 02ProbioticsStrong85% match
Certain probiotic strains may reduce stool frequency and duration in infectious and antibiotic-associated diarrhea by restoring microbial balance.
SuggestedMulti-strain probiotic (at least 10 billion CFU) - 03Lactobacillus RhamnosusModerate80% match
Lactobacillus rhamnosus GG may reduce the duration of acute infectious diarrhea, particularly in viral gastroenteritis, by adhering to the gut lining and modulating immune response.
SuggestedLactobacillus rhamnosus GG capsules - 04ZincModerate70% match
Zinc supports enterocyte repair and may shorten diarrhea duration, with the strongest data in deficiency states and in children in low-resource settings.
SuggestedZinc sulfate or zinc gluconate - 05Psyllium HuskModerate65% match
Soluble psyllium fiber absorbs excess water and adds stool bulk, which may firm loose stools in some chronic or functional diarrhea.
SuggestedPsyllium husk powder - 06L-GlutamineLimited58% match
L-glutamine is a primary fuel for enterocytes and may support mucosal repair, though evidence for treating routine diarrhea is limited.
SuggestedL-glutamine powder
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These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.