Aluminum/Magnesium Hydroxide and Ciprofloxacin: what the published research says
PubMed indexes 6 records that name Aluminum/Magnesium Hydroxide and Ciprofloxacin together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.
Every statement below is attributed to a named, dated, linked source.
This page lists published research relevant to Aluminum/Magnesium Hydroxide and Ciprofloxacin. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.
A study appearing here is not proof that an interaction exists. Two substances can be named together in a paper that never tested them in combination, and a source listed as background may cover only one of them.
Findings are quoted from each abstract as the authors wrote them. NutriStack has not re-analysed, pooled, or reconciled them, and they may disagree with each other.
NutriStack’s own interaction assessment for this pair is not published here. It has not completed qualified-human clinical review, so it is withheld from search. See the publication gate.
Nothing here is medical advice. Decisions about prescription medication and supplements belong with your prescriber or pharmacist, who can see your full regimen.
The research
6 studies naming Aluminum/Magnesium Hydroxide and Ciprofloxacin.
Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.
Antimicrobial agents and chemotherapy · 1992 · PMID 1503446
Clinical TrialRandomized Controlled Trial
“Urinary recovery of Cipro in the aluminum hydroxide treatment group was approximately one-fourth of that in the calcium carbonate group. Although calcium carbonate decreased absorption to a lesser extent than aluminum hydroxide, these data suggest that antacids containing either aluminum or calcium should not be given concomitantly with Cipro.”
Names both Aluminum/Magnesium Hydroxide and Ciprofloxacin in its title.
Clinical pharmacology and therapeutics · 1989 · PMID 2598571
Clinical TrialControlled Clinical Trial
“The extent of this interaction appears to increase as the time between administration of the two drugs decreases. Ranitidine is suggested as an alternative to antacids for patients receiving treatment with ciprofloxacin.”
Names both Aluminum/Magnesium Hydroxide and Ciprofloxacin in its title.
Journal of colloid and interface science · 2022 · PMID 34371426
“The proposed treatment system remediated 10 litters of 100 mg L-1 of ciprofloxacin solution with 100% overall removal efficiency. This treatment system could be a promising and practical solution to decrease ciprofloxacin concentration in different water bodies.”
Names both Aluminum/Magnesium Hydroxide and Ciprofloxacin in its title.
Journal of clinical pharmacology · 2002 · PMID 12092748
Clinical TrialRandomized Controlled Trial
“These findings suggest that when ciprofloxacin and calcium polycarbophil were coadministered concomitantly, a decrease of ciprofloxacin absorption was observed, and this action was caused by the formation of chelate complexes. Therefore, it seems clear that we should avoid the concomitant administration of ciprofloxacin and calcium polycarbophil.”
Names Aluminum/Magnesium Hydroxide and Ciprofloxacin together in an interaction, co-administration, or pharmacokinetic context.
Biopharmaceutics & drug disposition · 1997 · PMID 9008270
Clinical TrialRandomized Controlled Trial
“The data from the present study demonstrate that didanosine or ciprofloxacin can be added to a treatment regimen consisting of the other single agent and that cessation of treatment with one agent does not have an impact on the pharmacokinetics of the other drug. The dose of ciprofloxacin must be taken at least 2h prior to didanosine to avoid a clinically significant interaction with the antacids present in the didanosine formulation.”
Names Aluminum/Magnesium Hydroxide and Ciprofloxacin together in an interaction, co-administration, or pharmacokinetic context.
Names Aluminum/Magnesium Hydroxide and Ciprofloxacin together in an interaction, co-administration, or pharmacokinetic context.
Limitations
What this evidence cannot tell you.
Search-based evidence indexes have real limits, and it is worth being explicit about them:
Selection. These records were found by searching PubMed titles and abstracts for both substance names alongside interaction and pharmacokinetic terms. Relevant work that phrases things differently, or is not indexed in PubMed, will be missing.
No effect size. The quoted conclusions are the authors’ words about their own study. We have not extracted effect direction or magnitude, and a single study’s conclusion is not a consensus.
Population mismatch. Findings in healthy volunteers, animals, or a specific patient group may not transfer to you, your dose, or your formulation.
Absence is not safety. Few published studies means the combination is under-studied, which is not the same as established as safe.
Nearby evidence
Other pairs with published research.
Pages covering Aluminum/Magnesium Hydroxide or Ciprofloxacin alongside a different substance.
NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Aluminum/Magnesium Hydroxide, Ciprofloxacin, and several hundred other substances.
The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
