NSTK · 01.2026Independent supplement reference

Edition 1.0Updated August 1, 2026

Supplement × Prescription·Evidence index

Ciprofloxacin and Manganese: what the published research says

PubMed indexes 8 records that name Ciprofloxacin and Manganese together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Reviews & meta-analyses

Read the studies ↓ How we select sources

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Ciprofloxacin and Manganese. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

A study appearing here is not proof that an interaction exists. Two substances can be named together in a paper that never tested them in combination, and a source listed as background may cover only one of them.
Findings are quoted from each abstract as the authors wrote them. NutriStack has not re-analysed, pooled, or reconciled them, and they may disagree with each other.
NutriStack’s own interaction assessment for this pair is not published here. It has not completed qualified-human clinical review, so it is withheld from search. See the publication gate.
Nothing here is medical advice. Decisions about prescription medication and supplements belong with your prescriber or pharmacist, who can see your full regimen.

The research

8 studies naming Ciprofloxacin and Manganese.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Manganese-Doped Carbon Dots for Sensitive Fluorescence Detection of Ciprofloxacin in Environmental and Pharmaceutical Samples.

Biosensors · 2026 · PMID 42505433

Names both Ciprofloxacin and Manganese in its title.

Enhanced biogenic manganese oxide production and the removal of Cd(II) and ciprofloxacin via fungus-bacterium co-cultivation.

Environmental research · 2025 · PMID 40398697

Names both Ciprofloxacin and Manganese in its title.

Co-occurrence of cadmium and ciprofloxacin in environmental media decreases ciprofloxacin degradation by biogenic manganese oxides.

Environmental pollution (Barking, Essex : 1987) · 2025 · PMID 39644959

Names both Ciprofloxacin and Manganese in its title.

Biodegradation of ciprofloxacin by a manganese-oxidizing fungus Cladosporium sp. XM01: Performance and transcriptome analysis.

Journal of hazardous materials · 2025 · PMID 40344838

Names both Ciprofloxacin and Manganese in its title.

Ciprofloxacin affects nutrient removal in manganese ore-based constructed wetlands: Adaptive responses of macrophytes and microbes.

Journal of hazardous materials · 2024 · PMID 38761761

Names both Ciprofloxacin and Manganese in its title.

Manganese oxides activated peroxymonosulfate for ciprofloxacin removal: Effect of oxygen vacancies and chemical states.

Chemosphere · 2022 · PMID 35367499

Names both Ciprofloxacin and Manganese in its title.

Water-soluble manganese porphyrins as good catalysts for cipro- and levofloxacin degradation: Solvent effect, degradation products and DFT insights.

Chemosphere · 2021 · PMID 33360938

Names both Ciprofloxacin and Manganese in its title.

Ciprofloxacin removal by ultrasound-enhanced carbon nanotubes/permanganate process: In situ generation of free reactive manganese species via electron transfer.

Water research · 2021 · PMID 34246002

“Interestingly, CNTs could be well reused in the UCP process as more than 88.75% of ciprofloxacin was removed after five times reuse of CNTs. The UCP process provides a novel strategy for rapid contaminants removal in water treatment via continuous generation of free RMnS.”
Wang et al. · From the abstract

Names both Ciprofloxacin and Manganese in its title.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

Selection. These records were found by searching PubMed titles and abstracts for both substance names alongside interaction and pharmacokinetic terms. Relevant work that phrases things differently, or is not indexed in PubMed, will be missing.
No effect size. The quoted conclusions are the authors’ words about their own study. We have not extracted effect direction or magnitude, and a single study’s conclusion is not a consensus.
Population mismatch. Findings in healthy volunteers, animals, or a specific patient group may not transfer to you, your dose, or your formulation.
Absence is not safety. Few published studies means the combination is under-studied, which is not the same as established as safe.

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Ciprofloxacin, Manganese, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.