NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Prescription·Evidence index

Atorvastatin and Red Yeast Rice: what the published research says

PubMed indexes 4 records that name Atorvastatin and Red Yeast Rice together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Atorvastatin and Red Yeast Rice. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

4 studies naming Atorvastatin and Red Yeast Rice.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Red yeast rice and coenzyme Q10 as safe alternatives to surmount atorvastatin-induced myopathy in hyperlipidemic rats.

Canadian journal of physiology and pharmacology · 2014 · PMID 24896301

Animal study

“RYR maintained normal levels of heart ubiquinones, which are essential components for energy production in muscles. In conclusion, RYR and CoQ10 may offer alternatives to overcome atorvastatin-associated myopathy.”

Abdelbaset et al. · From the abstract

Names both Atorvastatin and Red Yeast Rice in its title.

Effect of "Natural Polypill", Xuezhikang on Serum Cholesterol Metabolism Markers in Early Menopausal Women with Hypercholesterolemia.

Chinese journal of integrative medicine · 2022 · PMID 34432203

Randomized Controlled Trial

“Xuezhikang may have more comprehensive effects on the markers of cholesterol synthesis and metabolism in early menopausal women with hypercholesterolemia through ergosterol and flavonoids in its "natural polypill."”

Feng et al. · Authors' conclusion

Names Atorvastatin and Red Yeast Rice together in an interaction, co-administration, or pharmacokinetic context.

Simvastatin monotherapy as a potential option for statin-associated muscle symptoms: a case report.

Journal of clinical pharmacy and therapeutics · 2016 · PMID 27425755

Case ReportsHuman subjects

“Our case suggests that patients with SAMS who are intolerant to a wide variety of statins may be successfully managed with simvastatin monotherapy.”

Qu et al. · Authors' conclusion

Names Atorvastatin and Red Yeast Rice together in an interaction, co-administration, or pharmacokinetic context.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Atorvastatin, Red Yeast Rice, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.