Supplement × Supplement·Evidence index
PubMed indexes 8 records that name Berberine and Red Yeast Rice together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.
Every statement below is attributed to a named, dated, linked source.
This page lists published research relevant to Berberine and Red Yeast Rice. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.
Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.
“This meta-analysis confirms that the nutraceutical combination containing berberine, policosanol, and red yeast rice has shown to be an effective product for the improvement of the lipid profile.”
Names both Berberine and Red Yeast Rice in its title.
Names both Berberine and Red Yeast Rice in its title.
“In this study the authors have demonstrated that combined nutraceuticals significantly reduce cholesterolemia and achieved acceptable plasma LDL-C levels in elderly hypercholesterolemic patients who were previously statin-intolerant. Combined nutraceuticals is also safe and well tolerated in these patients.”
Names both Berberine and Red Yeast Rice in its title.
“This NC reduces cholesterol levels. The reduction is associated with improved endothelial function and insulin sensitivity.”
Names both Berberine and Red Yeast Rice in its title.
“Red yeast rice products and Armolipid may be used as an alternative treatment in statin intolerant patients, especially in combination with ezetimibe. These nutraceutics can be also considered, as an adjunct to diet therapy in primary prevention of cardiovascular diseases in patients with mild and moderate hypercholesterolaemia. The opinion of experts on berberine and bergamot is ambiguous.”
Names both Berberine and Red Yeast Rice in its title.
“These considerations suggest that combined administration of RYR and berberine may provide a broader range of health protection than is afforded by prescription statin therapy, with lower risks for serious adverse effects compared with statins. Randomized, controlled trials (RCTs) assessing the effect of optimal intakes of RYR and berberine on serum lipids and other vascular risk factors are needed.”
Names both Berberine and Red Yeast Rice in its title.
“In patients with low- to moderate-risk hypercholesterolemia a nutraceutical combination in association with a hypolipidic diet significantly reduced total cholesterol and LDL-C levels and may favor the reaching the recommended cholesterol targets. ClinicalTrials.gov identifier: NCT02078167.”
Names both Berberine and Red Yeast Rice in its title.
Names both Berberine and Red Yeast Rice in its title.
Search-based evidence indexes have real limits, and it is worth being explicit about them:
NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Berberine, Red Yeast Rice, and several hundred other substances.
The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
