From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyEmerging evidence
What is happening. Both may lower lipids and glucose, which can be useful but may increase hypoglycemia risk with diabetes medications.
Mechanism. Complementary effects on AMPK, lipid metabolism, and glucose handling.
Recommendation. Monitor glucose and lipids; avoid aggressive stacking if using glucose-lowering prescriptions.
Stack Score
How it moves the number.
Effect on the composite score
If both Berberine and Bergamot (Citrus Bergamia) Extract are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Toth PP et al. Bergamot clinical application review. 2016.Needs sourceNo link