From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Prescription
Last verified
June 4, 2026
SynergyEmerging evidence
What is happening. Berberine may add modest lipid-lowering effects to Ezetimibe.
Mechanism. Pharmacodynamic additivity through complementary LDL cholesterol, triglyceride, bile acid, or glycemic pathways.
Recommendation. Use as part of the lipid plan, not as a substitute for prescribed therapy; recheck lipids after regimen changes.
Stack Score
How it moves the number.
Effect on the composite score
If both Berberine and Ezetimibe are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Clinical lipid guideline and supplement evidence reviews.Needs sourceNo link