From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Prescription
Last verified
June 4, 2026
CautionEmerging evidence
What is happening. Live probiotics rarely cause bacteremia or fungemia in severely immunosuppressed patients.
Mechanism. Reduced immune surveillance can permit translocation or invasive infection from live organisms.
Recommendation. Avoid unsupervised probiotics during intense immunosuppression, neutropenia, central lines, or severe illness.
Stack Score
How it moves the number.
Effect on the composite score
If both Azathioprine and Probiotics are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1U.S. National Library of Medicine. Imuran Azathioprine Tablets US Prescribing Information. 2026.Needs sourceNo link