Supplement × Prescription·a synergy·Emerging evidence
Vitamin K2 is sometimes used to support calcium-handling proteins, but it does not prevent calcitriol-induced hypercalcemia.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. Vitamin K2 is sometimes used to support calcium-handling proteins, but it does not prevent calcitriol-induced hypercalcemia.
Mechanism. Vitamin K-dependent proteins participate in bone and vascular mineral biology while calcitriol controls calcium and phosphate absorption.
Recommendation. Use only as adjunctive nutrition support and keep calcium monitoring unchanged.
Effect on the composite score
If both Calcitriol and Vitamin K2 are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
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