Supplement × Supplement·timing-sensitive·Emerging evidence
High doses of calcium can modestly reduce zinc absorption, so taking the calcium from Ca-AKG together with a zinc supplement may slightly lower zinc uptake.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. High doses of calcium can modestly reduce zinc absorption, so taking the calcium from Ca-AKG together with a zinc supplement may slightly lower zinc uptake.
Mechanism. Calcium can compete with zinc for intestinal absorption, an effect most pronounced at high calcium intakes taken in the same meal.
Recommendation. Separate Ca-AKG and zinc supplements by 1-2 hours if zinc status is a concern, particularly at higher calcium doses.
Space the doses apart by at least this window to avoid the conflict.
Effect on the composite score
If both Calcium Alpha-Ketoglutarate and Zinc are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
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