NutriStack
Ginkgo Biloba and Vitamin E, a caution.
Both have antiplatelet activity at higher doses; combined use raises bleeding risk in surgical and anticoagulated patients.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Ginkgo Biloba and Vitamin E
- Pair type
- Caution
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- −5 to your Stack Score (per scored caution row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Caution · Emerging evidence
Caution
What is happening. Both have antiplatelet activity at higher doses; combined use raises bleeding risk in surgical and anticoagulated patients.
Mechanism. Vitamin E above 400 IU/day modestly impairs platelet aggregation; ginkgo inhibits PAF.
Recommendation. Avoid high-dose vitamin E (above 400 IU) alongside ginkgo, particularly before surgery or with warfarin or DOACs.
Sources (2)
- Bone KM. Potential interaction of Ginkgo biloba leaf with antiplatelet or anticoagulant drugs: what is the evidence? Mol Nutr Food Res. 2008;52(7):764-71. PMID 18214851
- Booth SL et al. Effect of vitamin E supplementation on vitamin K status in adults with normal coagulation status. Am J Clin Nutr. 2004;80(1):143-8. PMID 15213041
Stack Score
How this pair moves the number.
Effect on the composite score
If both Ginkgo Biloba and Vitamin E are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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