NutriStack
Glycine and Taurine, a synergy.
Glycine and taurine are both inhibitory amino acids that together support relaxation and may aid sleep onset, including glycine's documented lowering of core body temperature before bed.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Glycine and taurine are both inhibitory amino acids that together support relaxation and may aid sleep onset, including glycine's documented lowering of core body temperature before bed.
Mechanism. Glycine is a full agonist at the inhibitory strychnine-sensitive glycine receptor, while taurine acts as a weaker (partial) agonist at that receptor and also activates GABA-A receptors, so both reinforce inhibitory neurotransmission in the brainstem and spinal cord.
Recommendation. Reasonable to combine for evening calm or sleep support. A common pairing is glycine 3g with taurine 0.5g to 2g taken 30 to 60 minutes before bed.
Sources (2)
- Albrecht J, Schousboe A. Taurine interaction with neurotransmitter receptors in the CNS. Neurochemical Research. 2005
- Bannai M, Kawai N. New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep. Journal of Pharmacological Sciences. 2012
Stack Score
How this pair moves the number.
Effect on the composite score
If both Glycine and Taurine are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
Check your full routine
One pair was the worked example. NutriStack runs every pair in your stack at once.
Drop in your supplements and prescriptions and the public database surfaces every interaction, synergy, timing rule, and contraindication, every one linked to its primary source.