From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyInsufficient evidence
What is happening. Zinc adequacy supports insulin storage and metabolic health, but direct Gymnema-zinc outcome data are limited.
Mechanism. Complementary support of insulin physiology.
Recommendation. Reasonable to combine at standard zinc doses without exceeding upper intake limits.
Stack Score
How it moves the number.
Effect on the composite score
If both Gymnema Sylvestre and Zinc are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Pothuraju R et al. Gymnema pharmacology review. 2014.Needs sourceNo link