From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyEmerging evidence
What is happening. NCFM is often used with other probiotic strains such as bifidobacteria, but efficacy is formulation-specific.
Mechanism. Complementary probiotic strains can affect fermentation, barrier, and immune pathways.
Recommendation. Use products listing full strain IDs and add one formula at a time.
Stack Score
How it moves the number.
Effect on the composite score
If both Lactobacillus acidophilus NCFM and Probiotics are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Ringel-Kulka T et al. NCFM and Bi-07 bloating trial. Journal of Clinical Gastroenterology. 2011.Needs sourceNo link