NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Prescription·Evidence index

Lithium and Zinc: what the published research says

PubMed indexes 8 records that name Lithium and Zinc together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Lithium and Zinc. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

8 studies naming Lithium and Zinc.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Research progress of functional MXene in inhibiting lithium/zinc metal battery dendrites.

RSC advances · 2024 · PMID 39184006

Review

“In the past two years, researchers have used MXene and MXene based materials in the anodes of zinc metal batteries and zinc ion hybrid capacitors, respectively, and made a series of important progressive steps in the inhibition of zinc dendrite growth. In this review, we summarize the research progress of functional MXenes in inhibiting the growth of lithium and zinc metal anode dendrites, and provide a brief overview and outlook on the current challenges of MXene materials…”

Wang et al. · From the abstract

Names both Lithium and Zinc in its title.

Influence of Lithium- and Zinc-Containing Bioactive Glasses on Pulpal Regeneration.

European journal of dentistry · 2023 · PMID 36812931

“Lithium- and zinc-containing bioactive glasses increased Axin2 and DSPP gene expression in SHEDs and can potentially enhance pulp mineralization and regeneration. Zinc-containing bioactive glasses are a promising candidate to be used as pulp capping materials.”

Tran et al. · Authors' conclusion

Names both Lithium and Zinc in its title.

Lithium and zinc levels along with oxidative status in myocardial infarction: A case-control study.

Heliyon · 2023 · PMID 38027575

“Our investigation revealed that Li had a protective effect against CAD by decreasing OS and increasing EF%. However, Zn at concentrations higher than 1810 μg/mL was found to be cytotoxic and increased the risk of MI through increased OS. Taken togather, it could be concluded that Li supplementation may decrease the risk of CAD.”

Shiri et al. · Authors' conclusion

Names both Lithium and Zinc in its title.

Effectiveness of Zinc Supplementation on Lithium-Induced Alterations in Thyroid Functions.

Biological trace element research · 2021 · PMID 32851540

Animal study

“Zinc has been observed to have the capability to nearly normalize the altered 2-h uptake of 131I, biological and effective half-lives of 131I, and circulating T4 levels that were altered after lithium treatment. The present study concludes that zinc may be an effective agent in normalizing the adverse effects caused by lithium on thyroid functions.”

Pathak et al. · From the abstract

Names both Lithium and Zinc in its title.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Lithium, Zinc, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.