Olive Leaf Extract and Quercetin, a synergy.
Olive leaf polyphenols and quercetin are complementary antioxidant and anti-inflammatory flavonoids that may also additively support healthy blood pressure and endothelial function.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Olive Leaf Extract and Quercetin
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Olive leaf polyphenols and quercetin are complementary antioxidant and anti-inflammatory flavonoids that may also additively support healthy blood pressure and endothelial function.
Mechanism. Both polyphenols scavenge free radicals and enhance endothelial nitric oxide availability while inhibiting inflammatory signaling, producing overlapping vascular and antioxidant benefits.
Recommendation. Reasonable to combine for antioxidant and vascular support; monitor blood pressure if also taking antihypertensives.
Sources (2)
- Larson AJ et al, Quercetin: a treatment for hypertension, Advances in Nutrition, 2012
- Lockyer S et al, Olive leaf phenolics and cardiovascular risk, European Journal of Nutrition, 2017
Stack Score
How this pair moves the number.
Effect on the composite score
If both Olive Leaf Extract and Quercetin are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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