Interaction databaseSupplement × SupplementReviewed May 2026

Olive Leaf Extract and Quercetin, a synergy.

Olive leaf polyphenols and quercetin are complementary antioxidant and anti-inflammatory flavonoids that may also additively support healthy blood pressure and endothelial function.

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

Sourcing standards·Evidence tiers

From the interaction database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances
Olive Leaf Extract and Quercetin
Pair type
Synergy
Evidence (highest tier)
Emerging
Source citations
2 sources
Stack Score effect
+2 to your Stack Score (per scored synergy row).
Scope
Supplement × Supplement
Last verified
May 30, 2026

Synergy · Emerging evidence

Synergy

What is happening. Olive leaf polyphenols and quercetin are complementary antioxidant and anti-inflammatory flavonoids that may also additively support healthy blood pressure and endothelial function.

Mechanism. Both polyphenols scavenge free radicals and enhance endothelial nitric oxide availability while inhibiting inflammatory signaling, producing overlapping vascular and antioxidant benefits.

Recommendation. Reasonable to combine for antioxidant and vascular support; monitor blood pressure if also taking antihypertensives.

Sources (2)
  1. Larson AJ et al, Quercetin: a treatment for hypertension, Advances in Nutrition, 2012
  2. Lockyer S et al, Olive leaf phenolics and cardiovascular risk, European Journal of Nutrition, 2017

Stack Score

How this pair moves the number.

Effect on the composite score

If both Olive Leaf Extract and Quercetin are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

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