NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Prescription·Evidence index

Valsartan and Zinc: what the published research says

PubMed indexes 3 records that name Valsartan and Zinc together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Valsartan and Zinc. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

3 studies naming Valsartan and Zinc.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Effects of metronidazole, tinidazole, captopril and valsartan on taste and serum levels of zinc and magnesium.

Saudi medical journal · 2009 · PMID 19198707

Human subjects54 participants

“It is concluded that metronidazole and tinidazole, but not captopril or valsartan resulted in a significant reduction of zinc level in rabbit, but not in human. Captopril and not valsartan caused severe degeneration in taste buds. Serum zinc level seems not to be related to taste buds changes.”

Salman et al. · Authors' conclusion

Names both Valsartan and Zinc in its title.

Pharmaco-nutrient interactions - a systematic review of zinc and antihypertensive therapy.

International journal of clinical practice · 2013 · PMID 23279674

Systematic ReviewHuman subjects

“The available evidence suggests that use of ACE inhibitors and angiotensin 2 receptor antagonists or thiazide diuretics have the potential to reduce zinc levels in hypertensive patients. Additional research using larger participant numbers and accounting for dietary zinc intakes are required.”

Braun et al. · Authors' conclusion

Names Valsartan and Zinc together in an interaction, co-administration, or pharmacokinetic context.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Valsartan, Zinc, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.