NutriStack
Symptom·Appearance·Reviewed May 30, 2026
Supplements for Dry, cracked lips / angular cheilitis.
When dry, cracked lips / angular cheilitis is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01Vitamin B2Moderate84% match
Riboflavin deficiency is a classic cause of angular cheilitis and cracked lips because it is needed for epithelial cell maintenance, so repletion can resolve deficiency-related cases.
SuggestedRiboflavin tablets, 5 to 10 mg daily - 02IronModerate76% match
Iron deficiency can cause angular cheilitis and mucosal changes by impairing epithelial cell turnover, so correcting deficiency often improves symptoms.
SuggestedIron bisglycinate, 25 to 30 mg, dosed per labs - 03ZincLimited70% match
Zinc is essential for skin and mucosal healing, and deficiency can present with cracked, inflamed skin at the lip corners.
SuggestedZinc picolinate, 10 to 15 mg daily with food - 04Vitamin B9Limited62% match
Folate supports rapid epithelial cell division, and deficiency can contribute to angular cheilitis and a sore mouth.
SuggestedFolate as methylfolate or folic acid, 400 mcg daily - 05Vitamin B7Limited55% match
Biotin contributes to skin and mucosal integrity, and severe deficiency can cause perioral dermatitis, though it is a rare cause of cracked lips.
SuggestedBiotin capsules, low dose around 30 to 100 mcg
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