Symptom·Cardiometabolic·Reviewed May 30, 2026
Supplements for High cholesterol.
When high cholesterol is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01BerberineModerate74% match
Berberine can support LDL and triglyceride control through AMPK-related and hepatic pathways.
SuggestedBerberine HCl - 02Berberine HClModerate67% match
Berberine HCl is the common clinical form used for metabolic and lipid support.
SuggestedBerberine HCl - 03Psyllium HuskStrong65% match
Soluble fiber lowers LDL by binding bile acids and reducing cholesterol reabsorption.
SuggestedPsyllium husk powder - 04Fish OilStrong62% match
Fish oil is more useful for triglycerides than for lowering LDL cholesterol.
SuggestedHigh-EPA/DHA fish oil - 05Vitamin B3Moderate54% match
Niacin can change lipids but side effects and risk-benefit tradeoffs limit casual use.
SuggestedNiacin - 06Garlic ExtractLimited42% match
Garlic has modest lipid-supportive effects in some studies.
SuggestedAged garlic extract
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These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.