NutriStack
Symptom·Cardiometabolic·Reviewed May 30, 2026
Supplements for High triglycerides.
When high triglycerides is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01Fish OilStrong90% match
EPA and DHA reduce hepatic VLDL synthesis and increase triglyceride clearance, producing dose-dependent reductions in serum triglycerides.
SuggestedHigh-EPA fish oil (2 to 4 g combined EPA and DHA daily) - 02Vitamin B3Moderate78% match
Niacin inhibits adipose lipolysis and hepatic triglyceride synthesis, lowering VLDL and circulating triglyceride output.
SuggestedImmediate-release niacin (nicotinic acid) - 03Krill OilModerate71% match
Provides EPA and DHA bound to phospholipids, which may aid incorporation and modestly lower triglycerides at lower omega-3 doses.
SuggestedPhospholipid-bound krill oil - 04BerberineLimited65% match
Berberine activates AMPK and modulates lipid metabolism, which may reduce triglycerides and improve the overall lipid profile in trials of variable quality.
SuggestedBerberine HCl (split dosing with meals) - 05Garlic ExtractLimited57% match
Garlic-derived organosulfur compounds may modestly influence hepatic lipid synthesis, with small and inconsistent effects on triglycerides.
SuggestedAged garlic extract (standardized) - 06L-CarnitineLimited55% match
By facilitating mitochondrial fatty acid transport and beta-oxidation, L-carnitine may modestly reduce circulating triglycerides in some populations.
SuggestedL-carnitine tartrate
Build your stack
Every match traces to a full profile.
These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.