Symptom·Cardiometabolic·Reviewed June 4, 2026
Supplements for High LDL cholesterol.
When high ldl cholesterol is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 0182% match
Competes with cholesterol absorption in intestinal micelles, lowering LDL-C.
SuggestedSterol or stanol esters with meals - 02Red Yeast RiceModerate78% match
Monacolin K inhibits HMG-CoA reductase, lowering LDL-C similarly to lovastatin when present.
SuggestedCitrinin-tested red yeast rice - 03Beta-GlucanStrong68% match
Oat and barley beta-glucans lower LDL-C through soluble fiber viscosity and bile acid handling.
SuggestedOat beta-glucan powder - 0458% match
Bergamot polyphenols may reduce cholesterol synthesis and improve LDL handling.
SuggestedStandardized bergamot polyphenol fraction - 05Beta-SitosterolStrong50% match
Plant sterols reduce intestinal cholesterol absorption.
SuggestedPlant sterol fortified food or supplement - 06TocotrienolsLimited38% match
May suppress cholesterol synthesis and reduce oxidative stress.
SuggestedGamma/delta tocotrienols
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These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.