NutriStack
Symptom·Appearance·Reviewed May 30, 2026
Supplements for Itchy skin / pruritus.
When itchy skin / pruritus is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01Fish OilModerate82% match
EPA and DHA dampen inflammatory eicosanoid signaling and support the skin lipid barrier, which may reduce itch in dry or eczema-prone skin.
SuggestedHigh-EPA triglyceride fish oil - 02Vitamin D3Limited74% match
Low vitamin D status is associated with atopic and inflammatory skin conditions, and repletion may modestly reduce itch when a deficiency is present.
SuggestedD3 (cholecalciferol) softgel - 03Evening Primrose OilLimited68% match
Provides gamma-linolenic acid (GLA) that may feed anti-inflammatory prostaglandin pathways and support barrier function in atopic skin.
SuggestedStandardized GLA evening primrose oil softgels - 04ProbioticsLimited64% match
Certain Lactobacillus and Bifidobacterium strains may modulate immune tone via the gut-skin axis, with some benefit reported for atopic itch.
SuggestedMulti-strain Lactobacillus and Bifidobacterium capsule - 05QuercetinLimited60% match
Quercetin can stabilize mast cells and reduce histamine release in lab studies, which may help itch with an allergic component.
SuggestedQuercetin phytosome or quercetin with bromelain - 06ZincLimited56% match
Zinc supports skin barrier repair and immune regulation, so correcting a deficiency may ease inflammatory itch.
SuggestedZinc bisglycinate (with food)
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These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.