NutriStack
Symptom·Sleep·Reviewed May 30, 2026
Supplements for Jet lag.
When jet lag is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01MelatoninStrong88% match
Melatonin shifts the circadian clock by signaling biological night, and well-replicated trials show it reduces jet lag severity when timed to the destination evening.
SuggestedLow-dose immediate-release melatonin, 0.5 to 3 mg near destination bedtime - 02Magnesium GlycinateLimited62% match
Magnesium supports relaxation and GABAergic tone, which may ease the muscle tension and restlessness that accompany disrupted travel sleep.
SuggestedMagnesium glycinate, 200 to 400 mg elemental magnesium before bed - 03L-TheanineLimited60% match
L-theanine promotes calm alertness by increasing alpha brain activity and modulating GABA and glutamate, which may ease travel-related anxiety and wind-down.
SuggestedL-theanine capsules, 100 to 200 mg as needed - 04AshwagandhaLimited55% match
Ashwagandha is an adaptogen that may lower cortisol and perceived stress, which could smooth the physiological strain of travel and schedule disruption.
SuggestedStandardized root extract such as KSM-66, 300 to 600 mg daily - 05Vitamin CLimited50% match
Vitamin C is an antioxidant that supports general immune and stress resilience during travel, but it has no established effect on the circadian clock.
SuggestedVitamin C, 250 to 500 mg daily
Build your stack
Every match traces to a full profile.
These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.