NutriStack
Symptom·Sleep·Reviewed May 30, 2026
Supplements for Restless legs.
When restless legs is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01IronStrong90% match
Low ferritin is a classic contributor to restless legs syndrome.
SuggestedIron bisglycinate - 02Magnesium GlycinateModerate63% match
Can help when restless legs overlap with nighttime muscle tension or low magnesium intake.
SuggestedMagnesium bisglycinate - 03Vitamin B12Limited46% match
Correcting low B12 can help neurologic symptoms that may mimic or worsen nighttime restlessness.
SuggestedMethylcobalamin - 04Vitamin D3Limited45% match
Low vitamin D status is associated with restless legs in some people.
SuggestedD3 (cholecalciferol) - 05MethylfolateLimited42% match
Folate support is sometimes used when low folate status overlaps with neurologic symptoms.
SuggestedMethylfolate
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These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.