NutriStack
Symptom·Mood·Reviewed May 30, 2026
Supplements for Mood swings.
When mood swings is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01Magnesium GlycinateModerate72% match
Magnesium supports GABA tone and HPA axis regulation, modulating reactivity.
SuggestedMagnesium glycinate, 200 to 400 mg elemental per day - 02Vitamin B6Moderate68% match
B6 is a cofactor for serotonin and GABA synthesis; classically used for PMS-related mood swings.
SuggestedP5P, 25 to 50 mg per day - 03InositolLimited62% match
Inositol modulates serotonergic signaling; small RCT evidence in mood disorders and PMS.
SuggestedMyo-inositol, 4 to 12 g per day - 04Fish OilModerate62% match
EPA modulates inflammation-driven mood symptoms; meta-analyses support 1 to 2 g EPA per day for depression adjunct.
SuggestedHigh-EPA fish oil, 1 to 2 g EPA per day - 05AshwagandhaModerate55% match
Lowers cortisol reactivity and modulates HPA axis volatility.
SuggestedKSM-66, 300 to 600 mg per day
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These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.