Bromelain and Turmeric/Curcumin, a synergy.
Bromelain is widely co-formulated with curcumin to add its own proteolytic anti-inflammatory effect, increasing the net anti-inflammatory action of the pair.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
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From the interaction database
What the row says.
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At a glance
- Substances
- Bromelain and Turmeric/Curcumin
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Bromelain is widely co-formulated with curcumin to add its own proteolytic anti-inflammatory effect, increasing the net anti-inflammatory action of the pair.
Mechanism. Bromelain is a proteolytic enzyme that independently reduces pro-inflammatory mediators, bradykinin, and tissue edema, complementing curcumin's inhibition of NF-kB driven inflammation; any effect on curcumin absorption in humans is not well established.
Recommendation. Can be taken together for inflammatory and recovery support; the two are frequently combined in joint and recovery formulas and need no time separation.
Sources (2)
- Brien S et al., Bromelain as a treatment for osteoarthritis: a review of clinical studies, Evidence-Based Complementary and Alternative Medicine, 2004
- Hewlings SJ and Kalman DS, Curcumin: A Review of Its Effects on Human Health, Foods, 2017
Stack Score
How this pair moves the number.
Effect on the composite score
If both Bromelain and Turmeric/Curcumin are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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