Supplement × Prescription·Evidence index
PubMed indexes 8 records that name Cannabis (THC-Dominant) and Quetiapine together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.
Every statement below is attributed to a named, dated, linked source.
This page lists published research relevant to Cannabis (THC-Dominant) and Quetiapine. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.
Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.
“The use of quetiapine to treat CUD was associated with an increased likelihood of heavy frequency use transitioning to moderate use, but not light use. The clinical significance of reductions in cannabis use, short of abstinence warrants further study.”
Names both Cannabis (THC-Dominant) and Quetiapine in its title.
“Quetiapine-XR was superior to placebo in reducing QIDS-SR-16 total score in patients with a recent ALC/CAN. Patients taking quetiapine-XR used less alcohol and cannabis than patients on placebo, suggesting that quetiapine-XR may be of use in patients with bipolar disorder accompanied by GAD and other comorbidities.”
Names both Cannabis (THC-Dominant) and Quetiapine in its title.
“These preliminary results are promising in that quetiapine treatment was tolerated by cannabis-dependent patients and associated with decreased cannabis use. The recommended maximum target dose for cannabis-dependent patients is 300 mg daily. These preliminary data support further evaluation of quetiapine as a treatment for cannabis dependence.”
Names both Cannabis (THC-Dominant) and Quetiapine in its title.
“However, quetiapine increased marijuana craving and marijuana self-administration during the relapse phase. These data do not suggest that quetiapine shows promise as a potential treatment for marijuana dependence.”
Names both Cannabis (THC-Dominant) and Quetiapine in its title.
Names both Cannabis (THC-Dominant) and Quetiapine in its title.
“The findings highlight the use of SGA for the treatment of psychotic symptoms in comorbidity with substance use. Future studies on people with dual diagnosis and focused on long-term evaluations are warranted and need to investigate the efficacy of newly introduced molecules, such as partial D2 agonists and longacting injectable antipsychotics.”
Names Cannabis (THC-Dominant) and Quetiapine together in an interaction, co-administration, or pharmacokinetic context.
“Clinicians should maintain a high index of suspicion, especially in cases resistant to conventional antiemetic therapy. Early recognition and patient education regarding cannabis cessation are critical to preventing recurrence and improving long-term outcomes.”
Names Cannabis (THC-Dominant) and Quetiapine together in an interaction, co-administration, or pharmacokinetic context.
“The results of the present study help to consolidate evidence of the usefulness of quetiapine as a treatment for adolescents with psychotic disorders. However, this study also highlights the issues encountered in treating this group, including the presence of comorbidities such as drug abuse.”
Names Cannabis (THC-Dominant) and Quetiapine together in an interaction, co-administration, or pharmacokinetic context.
Search-based evidence indexes have real limits, and it is worth being explicit about them:
NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Cannabis (THC-Dominant), Quetiapine, and several hundred other substances.
The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
