From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Pair type
Timing Sensitive
Scope
Supplement × Prescription
Last verified
June 4, 2026
Timing SensitiveStrong evidence
What is happening. Iron can reduce oral Cefdinir absorption when taken together.
Mechanism. Polyvalent cations can form poorly absorbed complexes in the gut or otherwise reduce oral antibiotic bioavailability.
Recommendation. Take cefdinir at least 2 hours before or after iron supplements; iron-fortified infant formula is handled separately by pediatric labeling.
Stack Score
How it moves the number.
Effect on the composite score
If both Cefdinir and Iron are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1DailyMed. Cefdinir US prescribing information. 2026.Needs sourceNo link