NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

Chlorella and Iron: what the published research says

PubMed indexes 8 records that name Chlorella and Iron together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Chlorella and Iron. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

8 studies naming Chlorella and Iron.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Arthrospira platensis and Chlorella vulgaris Consumption on Iron Status: A Systematic Review of In Vivo Studies.

Molecular nutrition & food research · 2025 · PMID 41255135

Systematic ReviewHuman subjects

“vulgaris are safe and effective microalgal supplements that enhance iron status and antioxidant defense, presenting promising alternatives to conventional iron therapy. However, longer-term human clinical trials are needed to validate these findings and determine optimal dosing strategies.”

Lacurezeanu et al. · From the abstract

Names both Chlorella and Iron in its title.

Iron-dependent mutualism between Chlorella sorokiniana and Ralstonia pickettii forms the basis for a sustainable bioremediation system.

ISME communications · 2022 · PMID 36407791

“These results demonstrate that iron bioavailability, often overlooked in cultivation, governs microalgal growth, enzymatic processes, and bioremediation potential. Our results suggest that phototrophic communities with an active association for iron and carbon exchange have the potential to overcome challenges associated with micronutrient availability, while scaling up bioremediation designs.”

Rawat et al. · From the abstract

Names both Chlorella and Iron in its title.

Contrary effects of phytoplankton Chlorella vulgaris and its exudates on mercury methylation by iron- and sulfate-reducing bacteria.

Journal of hazardous materials · 2022 · PMID 35398798

Research Support, U.S. Gov't, Non-P.H.S.

“In contrast, inhibition of methylation by FeRB was attributed to these bacteria incapable of competing with phytoplankton for Hg(II) binding and uptake. These observations suggest that phytoplankton could play different roles in affecting Hg(II) methylation by the two groups of anaerobic bacteria, FeRB and SRB, and thus shed additional light on how phytoplankton blooms may modulate MeHg production and bioaccumulation in the aquatic environment.”

Yin et al. · From the abstract

Names both Chlorella and Iron in its title.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Chlorella, Iron, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.