From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionEmerging evidence
What is happening. Both supply catechin-type polyphenols; high-dose stacks can increase GI and liver-safety concerns.
Mechanism. Additive catechin exposure and potential hepatic stress.
Recommendation. Avoid high-dose concentrated polyphenol stacking, especially in liver disease.
Stack Score
How it moves the number.
Effect on the composite score
If both Epicatechin and Green Tea Extract are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Schwarz NA et al. Epicatechin supplementation. Sports. 2018.Needs sourceNo link