NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

EGCG (Epigallocatechin Gallate) and Green Tea Extract: what the published research says

PubMed indexes 8 records that name EGCG (Epigallocatechin Gallate) and Green Tea Extract together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to EGCG (Epigallocatechin Gallate) and Green Tea Extract. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

8 studies naming EGCG (Epigallocatechin Gallate) and Green Tea Extract.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Green tea and green tea extract in oncological treatment: A systematic review.

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2023 · PMID 33593083

Systematic ReviewHuman subjects

“Green tea could be a possible complementary method for treating acute radiation-induced diarrhea. Due to limitations, further studies with higher methodological quality and larger sample sizes are needed.”

Wiese et al. · From the abstract

Names both EGCG (Epigallocatechin Gallate) and Green Tea Extract in its title.

Population nutrikinetics of green tea extract.

PloS one · 2018 · PMID 29466429

Clinical Trial

“Our data could help to gain a better understanding of the causes of variability of green tea effects and to improve the design of studies on the effects of green tea polyphenols in different health conditions. ClinicalTrials.gov: NCT01360320.”

Scholl et al. · From the abstract

Names both EGCG (Epigallocatechin Gallate) and Green Tea Extract in its title.

Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential.

Molecules (Basel, Switzerland) · 2025 · PMID 39942757

ReviewHuman subjects

“This review aims to summarize current knowledge on EGCG, emphasizing its critical role as a versatile natural bioactive agent with diverse clinical applications. Further exploration in both experimental and clinical settings is essential to fully unlock its therapeutic potential.”

Capasso et al. · From the abstract

Names both EGCG (Epigallocatechin Gallate) and Green Tea Extract in its title.

Epigallocatechin-Gallate (EGCG): An Essential Molecule for Human Health and Well-Being.

International journal of molecular sciences · 2025 · PMID 41009815

ReviewHuman subjects

“Emerging research also highlights its promise in aesthetic medicine for mitigating skin oxidative stress, improving skin brightness and neutralizing free radicals, responsible for wrinkles, hyperpigmentation, and loss of elasticity. The aim of this review is to examine the most recent literature on the wide-ranging clinical applications of Epigallocatechin-gallate (EGCG) and to assess its potential use as a daily foundational supplement to enhance both physical and mental…”

Rovaldi et al. · From the abstract

Names both EGCG (Epigallocatechin Gallate) and Green Tea Extract in its title.

The role of epigallocatechin gallate (EGCG) in uterine myomas.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2025 · PMID 40645013

ReviewHuman subjects

“Recently published results have shown the safety of this therapy and a positive effect on reducing fibroid size and treating resulting ailments. Our goal is to summarize current knowledge regarding the effectiveness of EGCG in treating fibroids and the possible mechanisms of its action.”

de Mezer et al. · From the abstract

Names both EGCG (Epigallocatechin Gallate) and Green Tea Extract in its title.

Effects of Green Tea Extract Epigallocatechin-3-Gallate on Oral Diseases: A Narrative Review.

Pathogens (Basel, Switzerland) · 2024 · PMID 39204235

ReviewHuman subjects

“EGCG prevents and manages various oral diseases through its antibacterial, anti-inflammatory, antioxidant, and antitumor properties. Compared to traditional treatments, EGCG generally exhibits lower tissue irritation and positive synergistic effects when combined with other therapies.”

Li et al. · Authors' conclusion

Names both EGCG (Epigallocatechin Gallate) and Green Tea Extract in its title.

The applications of epigallocatechin gallate (EGCG)-nanogold conjugate in cancer therapy.

Nanotechnology · 2023 · PMID 36535007

ReviewHuman subjects

“The nanoscale vehicle may improve the EGCG solubility and bioavailability while overcoming constraints and cellular barriers. This article reviewed the phytochemical EGCG-based gold nanoplatforms and their major anticancer applications, both individually, and in combination therapy in a few cases.”

Karimi-Shahri et al. · From the abstract

Names both EGCG (Epigallocatechin Gallate) and Green Tea Extract in its title.

A green tea extract catechin EGCg: Therapeutic potential for pediatric cardiomyopathies.

Pediatric discovery · 2023 · PMID 40625575

Review

“Given its therapeutic effects, EGCg might be a potential drug candidate for administration to patients with cardiomyopathy and heart failure. In this review, we will discuss the molecular mechanisms associated with the pathogenesis of diastolic dysfunction and summarize the pharmacological effects of EGCg on experimental animals and pediatric patients with cardiomyopathies and diastolic dysfunction.”

Quan et al. · From the abstract

Names both EGCG (Epigallocatechin Gallate) and Green Tea Extract in its title.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers EGCG (Epigallocatechin Gallate), Green Tea Extract, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.