NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

Flaxseed Oil and Vitamin D3: what the published research says

PubMed indexes 3 records that name Flaxseed Oil and Vitamin D3 together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Flaxseed Oil and Vitamin D3. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

3 studies naming Flaxseed Oil and Vitamin D3.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

An 8-Week Triple-Blind, Randomized, Placebo-Controlled Trial Evaluating High-Dose Vitamin D3 and Flaxseed Oil for Inflammation and Metabolic Health in Elderly Patients With Type 2 Diabetes: Implications for Clinical Management.

Journal of nutrition and metabolism · 2026 · PMID 42529699

“Cosupplementation with flaxseed oil and high-dose vitamin D3 significantly reduced systemic inflammation in elderly patients with T2DM. Exploratory findings further suggest potential benefits for oxidative stress, glycemic control, lipid profile, and physical quality of life, warranting confirmation in future trials. Trial Registration: Iranian Clinical Trials Register: IRCT20161022030424N8.”

Aghamohammadzadeh et al. · Authors' conclusion

Names both Flaxseed Oil and Vitamin D3 in its title.

Crystal structure of a secondary vitamin D3 binding site of milk beta-lactoglobulin.

Proteins · 2008 · PMID 18004750

Comparative StudyAnimal study

“This finding provides a new insight into the interaction between vitamin D(3) and beta-LG, in which the exosite may provide another route for the transport of vitamin D(3) in vitamin D(3) fortified dairy products. Atomic coordinates for the crystal structure of beta-LG-vitamin D(3) complex described in this work have been deposited in the PDB (access code 2GJ5).”

Yang et al. · From the abstract

Names Flaxseed Oil and Vitamin D3 together in an interaction, co-administration, or pharmacokinetic context.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Flaxseed Oil, Vitamin D3, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.