From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Pair type
Timing Sensitive
Scope
Supplement × Supplement
Last verified
June 4, 2026
Timing SensitiveEmerging evidence
What is happening. Fiber can delay or reduce mineral supplement absorption when taken simultaneously.
Mechanism. Fiber matrix and altered transit can reduce immediate mineral absorption reliability.
Recommendation. Separate iron supplements from FOS by at least 2 hours when treating deficiency.
TimingTiming & separation.
Space the doses apart by at least this window to avoid the conflict.
Stack Score
How it moves the number.
Effect on the composite score
If both Fructooligosaccharides (FOS) and Iron are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Birkeland E et al. Inulin-type fructans RCT. European Journal of Nutrition. 2020.Needs sourceNo link